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Medical Policies

Medical policies are documents that define the plan coverage for technologies, procedures and treatments. The statements of medical necessity in the policies, about whether a technology, procedure, treatment, supply, equipment, drug or other service improves the health outcome of the population for which said technology or treatment was designed are based on scientific evidence, clinical studies and professional opinions from our providers and recognized medical organizations.

Each document displayed on this website is provided for informational purposes only and is not an authorization, explanation of benefits, or contract. Receiving benefits is subject to satisfaction of all terms and conditions of coverage. Medical technology is constantly changing, and we reserve the right to periodically review and update our policies.

ID Title Last Review Next Review Description Access
11.003.004 Somatic Biomarker Testing (Including Liquid Biopsy) for Targeted Treatment in Metastatic Colorectal Cancer (KRAS, NRAS, BRAF, and HER2) Jul 17, 2024 Aug 20, 2024 Kras, nras, braf, or her2 testing of tumor tissue may be considered medically necessary for individuals with... View
11.003.006 PRUEBAS GENETICAS PARA EL TRATAMIENTO HELICOBACTER PYLORI May 12, 2016 Policy Archived La prueba genética para determinar polimorfismo en sistema enzimático citocromo p450 (cyp2c19) no procede... View
11.003.008 Cytochrome P450 Genotype-Guided Treatment Strategy Jul 17, 2024 Jul 20, 2025 Cytochrome p450 (cyp450) genotyping for the purpose of aiding in the choice of clopidogrel versus... View
11.003.009 Somatic Biomarker Testing (Including Liquid Biopsy) for Targeted Treatment in Non-Small-Cell Lung Cancer (EGFR, ALK, BRAF, ROS1, RET, MET, KRAS) Jul 22, 2024 Dec 20, 2024 Egfr testing analysis of tumor tissue for somatic variants in exons 18 through 21 (eg, g719x, l858r,... View
11.003.010 Genetic Testing of CADASIL Syndrome May 16, 2024 May 20, 2025 Genetic testing for a notch3 variant to confirm the diagnosis of cerebral autosomal dominant arteriopathy... View
11.003.011 Somatic Genetic Testing to Select Individuals with Melanoma or Glioma for Targeted Therapy (BRAF) Jul 19, 2024 Jul 20, 2025 Testing for braf v600 variants in individuals with unresectable or metastatic melanoma, or with resected... View
11.003.012 Genetic Testing for Inherited Thrombophilia Jun 18, 2024 Jun 20, 2025 Genetic testing for inherited thrombophilia, including testing for the factor v leiden variant, prothrombin... View
11.003.013 Genetic Testing for Rett Syndrome Jun 07, 2024 Jun 20, 2025 Genetic testing for rett syndrome-associated genes (eg, mecp2, foxg1, or cdkl5) may be considered medically... View
11.003.014 Noninvasive Fetal RHD Genotyping Using Cell-Free Fetal DNA Sep 07, 2023 Sep 20, 2024 Noninvasive fetal rhd genotyping using cell-free fetal dna is considered... View
11.003.015 Gene Expression Profile Testing and Circulating Tumor DNA Testing for Predicting Recurrence in Colon Cancer Sep 19, 2023 Sep 20, 2024 Gene expression assays for determining the prognosis of stage ii or iii colon cancer following surgery are... View
11.003.016 Genetic Testing for PTEN Hamartoma Tumor Syndrome Mar 08, 2024 Mar 20, 2025 Genetic testing for pten may be considered medically necessary to confirm the diagnosis when a patient has... View
11.003.017 Genetic Testing for Hereditary Hearing Loss May 12, 2024 May 20, 2025 Genetic testing for hereditary hearing loss genes (gjb2, gjb6, and other hereditary hearing loss–related... View
11.003.018 Chromosomal Microarray Testing for the Evaluation of Pregnancy Loss Sep 19, 2023 Sep 20, 2024 Chromosomal microarray testing of fetal tissue may be considered medically necessary for the evaluation of... View
11.003.020 Genetic Testing for Lactase Insufficiency Jun 13, 2024 Jun 20, 2025 The use of targeted mcm6 -13910c>t variant analysis for the prediction of lactase insufficiency is considered... View
11.003.021 Gene Expression Testing in the Evaluation of Patients with Stable Ischemic Heart Disease Apr 20, 2021 Policy Archived Gene expression testing in the evaluation of patients with stable ischemic heart disease is... View
11.003.022 Genetic Testing for Li-Fraumeni Syndrome Aug 16, 2023 Aug 20, 2024 Genetic testing for tp53 may be considered medically necessary to confirm a diagnosis of li-fraumeni syndrome... View
11.003.023 General Approach to Evaluating the Utility of Genetic Panels Jan 09, 2024 Jan 20, 2025 Genetic panels that use next-generation sequencing or chromosomal microarray analysis, and are classified in... View
11.003.025 Genetic Testing for Developmental Delay/Intellectual Disability, Autism Spectrum Disorder, and Congenital Anomalies Nov 16, 2023 Nov 20, 2024 Chromosomal microarray analysis may be considered medically necessary as first-line testing in the initial... View
11.003.026 Comprehensive Genomic Profiling for Selecting Targeted Cancer Therapies Nov 16, 2023 Nov 20, 2024 The use of comprehensive genomic profiling for selecting targeted cancer treatment is considered... View
11.003.027 Germline Genetic Testing for Gene Variants Associated With Breast Cancer in Individuals at High Breast Cancer Risk (CHEK2, ATM, and BARD1) Sep 13, 2023 Sep 20, 2024 Testing for chek2, atm, and bard1 variants in the assessment of breast cancer risk is considered... View

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