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Medical Policies

Medical policies are documents that define the plan coverage for technologies, procedures and treatments. The statements of medical necessity in the policies, about whether a technology, procedure, treatment, supply, equipment, drug or other service improves the health outcome of the population for which said technology or treatment was designed are based on scientific evidence, clinical studies and professional opinions from our providers and recognized medical organizations.

Each document displayed on this website is provided for informational purposes only and is not an authorization, explanation of benefits, or contract. Receiving benefits is subject to satisfaction of all terms and conditions of coverage. Medical technology is constantly changing, and we reserve the right to periodically review and update our policies.

ID Title Last Review Next Review Description Access
11.003.035 Assays of Genetic Expression in Tumor Tissue as a Technique to Determine Prognosis in Patients with Breast Cancer Dec 06, 2023 Dec 20, 2024 The use of the 21-gene reverse transcriptase-polymerase chain reaction (rt-pcr) assay (ie, oncotype dx),... View
11.003.036 Genetic Testing for Familial Cutaneous Malignant Melanoma Apr 12, 2023 Apr 20, 2024 Genetic testing for genes associated with familial cutaneous malignant melanoma or associated with... View
11.003.037 Biomarker Testing in Risk Assessment and Management of Cardiovascular Disease Jan 19, 2024 Jan 20, 2025 For testing performed as a panel, see evidence review 11.001.015. genetic counseling experts recommend... View
11.003.038.html Biomarker Genes for Detection of Lymph Node metastases in Breast Cancer May 15, 2019 Policy Archived Evaluation of biomarker genes is considered investigational for detection of lymph node metastases in... View
11.003.039 Pharmacogenomic and Metabolite Markers for Patients Treated With Thiopurines Dec 20, 2023 Dec 20, 2024 One time genotypic or phenotypic analysis of thiopurine methyltransferase (tpmt) and nudix hydrolase (nudt15)... View
11.003.040 Genetic Testing for Alzheimer Disease Nov 16, 2023 Nov 20, 2024 Targeted genetic testing for a known familial variant in the presenilin (psen) genes or amyloid-beta... View
11.003.042 Genetic Testing for Cardiac Ion Channelopathies Feb 13, 2024 Feb 20, 2025 Long qt syndrome genetic testing to confirm a diagnosis of congenital long qt syndrome (lqts) may be... View
11.003.046 Genetic Testing for FMR1 Variants (Including X Syndrome) Feb 13, 2024 Feb 20, 2025 Genetic testing for fragile x mental retardation 1 gene (fmr1) variants may be considered medically... View
11.003.047 Gene Expression-Based Assays for Cancers of Unknown Primary Apr 13, 2023 Apr 20, 2024 Gene expression profiling is considered investigational to evaluate the site of origin of a tumor of... View
11.003.048 Carrier Screening for Genetic Diseases Oct 18, 2023 Oct 20, 2024 Targeted risk-based carrier screening targeted carrier screening for x-linked and autosomal recessive... View
11.003.049 Genetic Testing for Diagnosis and Management of Mental Health Conditions Aug 17, 2023 Aug 20, 2024 Genetic testing for diagnosis and management of mental health disorders is considered investigational in... View
11.003.050 Genetic Testing for Epilepsy Mar 14, 2023 Mar 20, 2024 Genetic testing for genes associated with infantile- and early-childhood onset epilepsy syndromes in... View
11.003.051 Gene Expression Profiling and Protein Biomarkers for Prostate Cancer Management Dec 06, 2023 Dec 20, 2024 Use of gene expression analysis and protein biomarkers to guide management of prostate cancer is considered... View
11.003.052 Molecular Markers in Fine Needle Aspirates of the Thyroid Sep 11, 2023 Sep 20, 2024 For individuals who have thyroid nodules without strong clinical or radiologic findings suggestive of... View
11.003.053 Whole Exome and Whole Genome Sequencing for Diagnosis of Genetic Disorders Apr 19, 2023 Apr 20, 2024 Standard whole exome sequencing, with trio testing when possible (see policy guidelines), may be considered... View
11.003.056 Genetic Testing for a Thalassemia Jul 05, 2023 Jul 20, 2024 Genetic testing to confirm a diagnosis of α-thalassemia is considered investigational. genetic testing... View
11.003.057 Genetic Testing for Fanconi Anemia Jan 08, 2024 Jan 20, 2025 Genetic testing for the diagnosis of fanconi anemia may be considered medically necessary when the... View
11.003.059 Genetic Testing for Hereditary Pancreatitis Mar 14, 2023 Mar 20, 2024 Genetic testing for hereditary pancreatitis may be considered medically necessary for patients aged 18 years... View
11.003.060  Genetic Testing for FLT3, NPM1, and CEBPA Variants in Cytogenetically Normal Acute Myeloid Leukemia Feb 20, 2024 Feb 20, 2025 Genetic testing for flt3 internal tandem duplication (flt3-itd), npm1, andcebpa variants may be considered... View
11.003.062 General Approach to Genetic Testing Jan 09, 2024 Jan 20, 2025 Genetic testing classified in one of the categories below may be considered medically necessary when all... View
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