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Medical Policies

Medical policies are documents that define the plan coverage for technologies, procedures and treatments. The statements of medical necessity in the policies, about whether a technology, procedure, treatment, supply, equipment, drug or other service improves the health outcome of the population for which said technology or treatment was designed are based on scientific evidence, clinical studies and professional opinions from our providers and recognized medical organizations.

Each document displayed on this website is provided for informational purposes only and is not an authorization, explanation of benefits, or contract. Receiving benefits is subject to satisfaction of all terms and conditions of coverage. Medical technology is constantly changing, and we reserve the right to periodically review and update our policies.

ID Title Last Review Next Review Description Access
11.003.101 Genetic Testing for Alpha 1 – Antitrypsin Deficiency Feb 13, 2024 Feb 20, 2025 Genetic testing for alpha1-antitrypsin deficiency may be considered medically necessary when either of the... View
11.003.102 Genetic Testing for Neurofibromatosis Feb 09, 2024 Feb 20, 2025 Genetic testing for neurofibromatosis type 1 (nf1) or neurofibromatosis type 2 (nf2) pathogenic variants... View
11.003.103 Gene Therapy for Inherited Retinal Dystrophy Feb 13, 2024 Feb 20, 2025 Adeno-associated virus vector-based gene therapy via subretinal injection with voretigene neparvovec is... View
11.003.104 Genetic Testing for Lipoprotein(a) Variant(s) as a Decision Aid for Aspirin Treatment Dec 28, 2021 Policy Archived The use of genetic testing for the lpa rs3798220 allele (lpa-aspirin genotype) is considered investigational... View
11.003.105 Microarray-Based Gene Expression Profile Testing for Multiple Myeloma Risk Stratification Nov 17, 2023 Nov 20, 2024 Microarray-based gene expression profile testing for multiple myeloma is considered investigational for all... View
11.003.106 Genetic Testing for Heterozygous Familial Hypercholesterolemia Feb 13, 2024 Feb 20, 2025 Genetic testing to confirm a diagnosis of familial hypercholesterolemia (fh) may be considered medically... View
11.003.107 Germline Genetic Testing for Pancreatic Cancer Susceptibility Genes (ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, and TP53) Mar 11, 2024 Mar 20, 2025 Genetic testing for brca1, brca2, and palb2 variants to guide selection for treatment with platinum-based... View
11.003.108 Measurement of Serum Antibodies to Selected Biologic Agent    Dec 20, 2023 Dec 20, 2024 Measurement of antidrug antibodies in an individual receiving treatment with a biologic agent, either alone... View
11.003.109 Human Leukocyte Antigen Testing for Celiac Disease Dec 06, 2023 Dec 20, 2024 Hla-dq2 and hla-dq8 testing may be considered medically necessary to rule out celiac disease in: patients... View
11.003.110 Genetic Testing for Statin-Induced Myopathy Dec 07, 2023 Dec 20, 2024 Genetic testing for the presence of variants in the slco1b1 gene to identify patients at risk of... View
11.003.111 Next Generation Sequencing for the Assessment of Measurable Residual Disease Jan 09, 2024 Jan 20, 2025 Next-generation sequencing (eg clonoseq) to detect measurable residual disease (mrd) at a threshold of... View
11.003.130 Acupuncture for Pain Management, Nausea and Vomiting, and Opioid Dependence Dec 14, 2023 Dec 20, 2024 Acupuncture may be considered medically necessary for treatment of episodic migraines and/or tension-type... View
11.003.131 Sphenopalatine Ganglion Block for Headache Dec 07, 2023 Dec 20, 2024 Sphenopalatine ganglion blocks are considered investigational for all indications, including but not limited... View
11.003.133 Serologic Genetic and molecular Screening for Colorectal Cancer Aug 17, 2023 Aug 20, 2024 Sept9 methylated dna testing (eg, colovantage®, epi procolon®) is considered investigational for colorectal... View
11.003.134 Molecular Testing for Germline Variants Associated with Ovarian Cancer (BRIP1, RAD51C, RAD51D, NBN) Sep 13, 2023 Sep 20, 2024 Testing for germline brip1, rad51c, and rad51d variants for ovarian cancer risk assessment in adults may... View
11.003.135 Germline and Somatic Biomarker Testing (Including Liquid Biopsy) for Targeted Treatment in Breast Cancer (BRCA1, BRCA2, PIK3CA, Ki-67, RET, BRAF, ESR1) Jan 17, 2024 Jan 20, 2024 Brca1 and brca2 testing genetic testing for brca1 or brca2 germline variants may be... View
11.003.136 Tumor-informed Circulating Tumor DNA Testing for Cancer Management May 12, 2024 May 20, 2025 Tumor-informed circulating tumor dna testing (e.g., signatera) is considered investigational for all... View
11.003.137 Germline Genetic Testing for Hereditary Diffuse Gastric Cancer (CDH1, CTNNA1) Sep 20, 2023 Sep 20, 2024 Germline genetic testing for cdh1 variants to identify individuals with or at risk for hereditary diffuse... View
11.003.138 Germline and Somatic Biomarker Testing (Including Liquid Biopsy) for Targeted Treatment and Immunotherapy in Prostate Cancer (BRCA1/2, Homologous Recombination Repair Gene Alterations) Oct 11, 2023 Oct 20, 2024 Germline brca1/2 variant analysis for individuals with metastatic castrate-resistant prostate cancer (mcrpc)... View
11.003.139 Germline and Somatic Biomarker Testing (Including Liquid Biopsy) for Targeted Treatment in Ovarian Cancer (BRCA1, BRCA2, Homologous Recombination Deficiency) Oct 11, 2023 Oct 20, 2024 Germline brca1/2 variant analysis may be considered medically necessary for individuals with advanced... View

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