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Medical Policies

Medical policies are documents that define the plan coverage for technologies, procedures and treatments. The statements of medical necessity in the policies, about whether a technology, procedure, treatment, supply, equipment, drug or other service improves the health outcome of the population for which said technology or treatment was designed are based on scientific evidence, clinical studies and professional opinions from our providers and recognized medical organizations.

Each document displayed on this website is provided for informational purposes only and is not an authorization, explanation of benefits, or contract. Receiving benefits is subject to satisfaction of all terms and conditions of coverage. Medical technology is constantly changing, and we reserve the right to periodically review and update our policies.

ID Title Last Review Next Review Description Access
11.001.041  Drug Testing in Pain Management and Substance Use Disorder Treatment Dec 09, 2024 Dec 20, 2025 In outpatient pain management, presumptive (i.e. immunoassay) drug testing may be considered medically... View
11.001.042 Fecal Calprotectin Testing Jan 15, 2025 Jan 20, 2026 Fecal calprotectin testing may be considered medically necessary for the evaluation of individuals when the... View
11.001.044 Antigen Leukocyte Antibody Test Nov 15, 2024 Nov 20, 2025 The antigen leukocyte antibody test (alcat) is intended to diagnose intolerance to foods and other... View
11.001.046 Maternal Serum Biomarkers for Prediction of Adverse Obstetric Outcomes Mar 19, 2024 Mar 20, 2025 The use of maternal serum biomarker tests with or without additional algorithmic analysis for prediction of... View
11.001.047 Multicancer Early Detection Testing Jul 19, 2024 Jul 20, 2025 The use of multicancer early detection (mced) tests (e.g., galleri) is considered investigational for cancer... View
11.002.001 Systems Pathology in Prostate Cancer Dec 10, 2020 Policy Archived Use of tests utilizing systems pathology that include cellular and biologic features of a tumor is considered... View
11.002.003 Molecular Testing for the Management of Pancreatic Cysts and Solid Pancreaticobiliary Lesions Dec 26, 2024 Dec 20, 2025 Molecular testing using the pathfindertg system is considered investigational for all indications including... View
11.002.004 Cervical Cancer Screening Technologies With Pap and HPV Apr 28, 2022 Policy Archived The following refers to average-risk asymptomatic women aged 21 to 65: preparation of papanicolaou (pap)... View
11.003.001 Laboratory Tests Post Transplant and for Heart Failure Nov 15, 2024 Nov 20, 2025 The use of the presage st2 assay to evaluate the prognosis of individuals diagnosed with chronic heart... View
11.003.002 Genetic Testing for Predisposition to Inherited Hypertrophic Cardiomyopathy Apr 15, 2024 Apr 20, 2025 Genetic testing for predisposition to hypertrophic cardiomyopathy may be considered medically necessary for... View
11.003.003 Multimarker Serum Testing Related to Ovarian Cancer Jan 20, 2025 Jan 20, 2026 All uses of the ova1, overa, and roma tests are investigational, including but not limited to:... View
11.003.004 Somatic Biomarker Testing (Including Liquid Biopsy) for Targeted Treatment in Metastatic Colorectal Cancer (KRAS, NRAS, BRAF, and HER2) Aug 23, 2024 Aug 20, 2025 Kras, nras, braf, ntrk, or her2 testing of tumor tissue may be considered medically necessary for individuals... View
11.003.006 PRUEBAS GENETICAS PARA EL TRATAMIENTO HELICOBACTER PYLORI May 12, 2016 Policy Archived La prueba genética para determinar polimorfismo en sistema enzimático citocromo p450 (cyp2c19) no procede... View
11.003.008 Cytochrome P450 Genotype-Guided Treatment Strategy Jul 17, 2024 Jul 20, 2025 Cytochrome p450 (cyp450) genotyping for the purpose of aiding in the choice of clopidogrel versus... View
11.003.009 Somatic Biomarker Testing (Including Liquid Biopsy) for Targeted Treatment in Non-Small-Cell Lung Cancer (EGFR, ALK, BRAF, ROS1, RET, MET, KRAS, NTRK).  Dec 05, 2024 Dec 20, 2025 Egfr testing analysis of tumor tissue for somatic variants in exons 18 through 21 (eg, g719x, l858r,... View
11.003.010 Genetic Testing of CADASIL Syndrome May 16, 2024 May 20, 2025 Variants in the notch3 gene have been causally associated with cerebral autosomal dominant arteriopathy with... View
11.003.011  Somatic Genetic Testing to Select Individuals with Melanoma or Glioma for Targeted Therapy (BRAF) Aug 15, 2024 Jul 20, 2025 Testing for braf v600 variants in individuals with unresectable or metastatic melanoma, or with resected... View
11.003.012 Genetic Testing for Inherited Thrombophilia Jun 18, 2024 Jun 20, 2025 Genetic testing for inherited thrombophilia, including testing for the factor v leiden variant, prothrombin... View
11.003.013 Genetic Testing for Rett Syndrome Jul 17, 2024 Policy Archived Genetic testing for rett syndrome-associated genes (eg, mecp2, foxg1, or cdkl5) may be considered medically... View
11.003.014 Noninvasive Fetal RHD Genotyping Using Cell-Free Fetal DNA Sep 12, 2024 Sep 20, 2025 Noninvasive fetal rhd genotyping using cell-free fetal dna is considered investigational.... View

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