Minimally Invasive Breast Biopsy (MIBB) is a breast biopsy that is done with a needle to obtain a diagnosis of a breast abnormality. There are three different types of MIBB. Breast biopsy methods include core needle biopsy (CNB), fine needle aspiration (FNA), surgical biopsy, and skin punch biopsy. Based on the prebiopsy imaging, the radiologist makes an assessment of which approach will yield the highest likelihood of success, while considering patient safety and comfort. The imaging findings are correlated with the clinical exam to determine whether the chosen biopsy target(s) account for the clinical abnormality. The requirements of subsequent therapy and/or clinical trial (eg, marker clip placement, tissue banking) are additional factors that are included in biopsy planning. The choice of imaging guidance depends upon the modality on which the lesion is best visualized and whether it is palpable. Patient factors such as tolerance for positioning (eg, prone position is usually needed for stereotactic or magnetic resonance imaging [MRI] guidance) are also considered. <a id="
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