Preimplantation genetic diagnosis may be considered medically necessary as an adjunct to in vitro fertilization (IVF) in couples not known to be infertile who meet one of the criteria listed below.
For evaluation of an embryo at an identified elevated risk of a genetic disorder such as when:
Both partners are known carriers of a single-gene autosomal recessive disorder
One partner is a known carrier of a single-gene autosomal recessive disorder, and the partners have an offspring who has been diagnosed with that recessive disorder
One partner is a known carrier of a single-gene autosomal dominant disorder
One partner is a known carrier of a single X-linked disorder, or
For evaluation of an embryo at an identified elevated risk of structural chromosomal abnormality such as for a:
Parent with balanced or unbalanced chromosomal translocation.
Preimplantation genetic diagnosis as an adjunct to IVF is considered investigational in patients or couples who are undergoing IVF in all situations other than those specified above.
Preimplantation genetic screening as an adjunct to IVF is considered investigational in patients or couples who are undergoing IVF in all situations.
