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Noninvasive Prenatal Screening for Fetal Aneuploidies, Microdeletions, Single-Gene Disorders and Twin Zygosity Using Cell-Free Fetal DNA

Nucleic acid sequencing-based testing of maternal plasma to screen for trisomy 21, 18, and 13 may be considered medically necessary in individuals with singleton pregnancies.
Nucleic acid sequencing-based testing of maternal plasma for fetal sex chromosome aneuploidies is considered investigational.

Nucleic acid sequencing-based testing of maternal plasma for trisomy 21 is considered investigational in individuals with twin or multiple pregnancies.

Nucleic acid sequencing-based testing of maternal plasma for microdeletions is considered investigational.

Nucleic acid sequencing-based testing of maternal plasma for twin zygosity is considered investigational.

Vanadis NIPT of maternal plasma to screen for trisomy 21, 18 and 13 is considered investigational in all situations.

Vistara NIPT of maternal plasma to screen for single-gene disorders is considered investigational in all situations.

Nucleic acid sequencing-based testing of maternal plasma, other than in the situations specified above, is considered investigational.

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