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Medical Policies

Medical policies are documents that define the plan coverage for technologies, procedures and treatments. The statements of medical necessity in the policies, about whether a technology, procedure, treatment, supply, equipment, drug or other service improves the health outcome of the population for which said technology or treatment was designed are based on scientific evidence, clinical studies and professional opinions from our providers and recognized medical organizations.

Each document displayed on this website is provided for informational purposes only and is not an authorization, explanation of benefits, or contract. Receiving benefits is subject to satisfaction of all terms and conditions of coverage. Medical technology is constantly changing, and we reserve the right to periodically review and update our policies.

ID Title Last Review Next Review Description Access
11.003.089 Circulating Tumor DNA and Circulating Tumor Cells for Cancer Management (Liquid Biopsy) Sep 20, 2024 Sep 20, 2025 The use of circulating tumor dna and/or circulating tumor cells is considered investigational for all... View
11.003.090 RATIONALE Mar 15, 2024 Mar 20, 2025 Gene expression profiling for uveal melanoma with decisiondx-um is medically necessary for patients with... View
11.003.092 Proteogenomic Testing for Patients With Cancer Jul 08, 2024 Jul 20, 2025 Proteogenomic testing (see policy guidelines section) of individuals with cancer (including, but not limited... View
11.003.093 Genetic Testing for Mitochondrial Disorders Oct 08, 2024 Oct 20, 2025 Genetic testing to establish a genetic diagnosis of a mitochondrial disorder may be considered medically... View
11.003.094 Serum Biomarker Panel Testing for Systemic Lupus Erythematosus and Other Connective Tissue Diseases Jul 08, 2024 Jul 20, 2025 Serum biomarker panel testing with proprietary algorithms and/or index scores for the diagnosis of systemic... View
11.003.095 Genotype-Guided Tamoxifen Treatment Sep 13, 2024 Sep 20, 2025 Genotyping to determine cytochrome p450 2d6 (cyp2d6) variants is considered investigational for the purpose... View
11.003.096 Miscellaneous Genetic and Molecular Diagnostic Tests Aug 12, 2024 Aug 20, 2025 All tests listed in this policy are considered investigational and grouped according to the categories of... View
11.003.097 Gene Expression Profiling for Cutaneous Melanoma Jun 07, 2024 Jun 20, 2025 Gene expression testing, including but not limited to the pigmented lesion assay, in the evaluation of... View
11.003.098 Use of Common Genetic Variants (Single Nucleotide Variants) to Predict Risk of Nonfamilial Breast Cancer Nov 15, 2024 Nov 20, 2025 Testing for 1 or more single nucleotide variants to predict an individual’s risk of breast cancer is... View
11.003.099 Circulating Tumor DNA for Management of Non-Small-Cell Lung Cancer (Liquid Biopsy) Dec 10, 2021 Policy Archived Proteomic testing has been proposed as a way to predict survival outcomes, as well as the response to and... View
11.003.100 DNA-Based Testing for Adolescent Idiopathic Scoliosis Mar 05, 2021 Policy Archived Dna-based prognostic testing for adolescent idiopathic scoliosis is... View
11.003.101 Genetic Testing for Alpha 1 – Antitrypsin Deficiency Feb 13, 2024 Feb 20, 2025 Genetic testing for alpha1-antitrypsin deficiency may be considered medically necessary when either of the... View
11.003.102 Genetic Testing for Neurofibromatosis Feb 05, 2025 Feb 20, 2026 Genetic testing for neurofibromatosis type 1 (nf1) or neurofibromatosis type 2 (nf2) pathogenic variants... View
11.003.103 Gene Therapy for Inherited Retinal Dystrophy Feb 13, 2024 Feb 20, 2025 Adeno-associated virus vector-based gene therapy via subretinal injection with voretigene neparvovec is... View
11.003.104 Genetic Testing for Lipoprotein(a) Variant(s) as a Decision Aid for Aspirin Treatment Dec 28, 2021 Policy Archived Lipoprotein(a) (lpa) is a lipid-rich particle similar to low-density lipoprotein and has been determined to... View
11.003.105 Microarray-Based Gene Expression Profile Testing for Multiple Myeloma Risk Stratification Dec 05, 2024 Nov 20, 2025 Microarray-based gene expression profile testing for multiple myeloma is considered investigational for all... View
11.003.106 Genetic Testing for Heterozygous Familial Hypercholesterolemia Nov 12, 2024 Nov 20, 2025 Genetic testing to confirm a diagnosis of familial hypercholesterolemia (fh) may be considered medically... View
11.003.107 Germline Genetic Testing for Pancreatic Cancer Susceptibility Genes (ATM, BRCA1, BRCA2, CDKN2A, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, STK11, and TP53) Dec 16, 2024 Mar 20, 2025 Genetic testing for brca1, brca2, and palb2 variants to guide selection for treatment with platinum-based... View
11.003.108 Measurement of Serum Antibodies to Selected Biologic Agent    Dec 20, 2024 Dec 20, 2025 Measurement of antidrug antibodies in an individual receiving treatment with a biologic agent, either alone... View
11.003.109 Human Leukocyte Antigen Testing for Celiac Disease Dec 09, 2024 Dec 20, 2025 Hla-dq2 and hla-dq8 testing may be considered medically necessary to rule out celiac disease in: patients... View

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