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Medical Policies

Medical policies are documents that define the plan coverage for technologies, procedures and treatments. The statements of medical necessity in the policies, about whether a technology, procedure, treatment, supply, equipment, drug or other service improves the health outcome of the population for which said technology or treatment was designed are based on scientific evidence, clinical studies and professional opinions from our providers and recognized medical organizations.

Each document displayed on this website is provided for informational purposes only and is not an authorization, explanation of benefits, or contract. Receiving benefits is subject to satisfaction of all terms and conditions of coverage. Medical technology is constantly changing, and we reserve the right to periodically review and update our policies.

ID Title Last Review Next Review Description Access
11.003.037 Biomarker Testing in Risk Assessment and Management of Cardiovascular Disease Jan 20, 2025 Jan 20, 2026 Measurement of nontraditional lipid and non-lipid biomarkers (ie, apolipoprotein b, apolipoprotein ai,... View
11.003.038 Biomarker Genes for Detection of Lymph Node metastases in Breast Cancer May 15, 2019 Policy Archived Evaluation of biomarker genes is considered investigational for detection of lymph node metastases in... View
11.003.039 Pharmacogenomic and Metabolite Markers for Patients Treated With Thiopurines Dec 20, 2024 Dec 20, 2025 One time genotypic or phenotypic analysis of thiopurine methyltransferase (tpmt) and nudix hydrolase (nudt15)... View
11.003.040 Genetic Testing for Alzheimer Disease Nov 22, 2024 Nov 20, 2025 Targeted genetic testing for a known familial variant in the presenilin (psen) genes or amyloid-beta... View
11.003.042 Genetic Testing for Cardiac Ion Channelopathies Feb 13, 2024 Feb 20, 2025 Long qt syndrome genetic testing to confirm a diagnosis of congenital long qt syndrome (lqts) may be... View
11.003.046 Genetic Testing for FMR1 Variants (Including Fragile X Syndrome) Nov 26, 2024 Feb 20, 2025 Genetic testing for fragile x mental retardation 1 gene (fmr1) variants may be considered medically... View
11.003.047 Gene Expression-Based Assays for Cancers of Unknown Primary Apr 15, 2024 Apr 20, 2025 Gene expression profiling is considered investigational to evaluate the site of origin of a tumor of unknown... View
11.003.048 Carrier Screening for Genetic Diseases Oct 10, 2024 Oct 20, 2025 Targeted risk-based carrier screening targeted carrier screening for x-linked and autosomal recessive... View
11.003.049 Genetic Testing for Diagnosis and Management of Mental Health Conditions Aug 20, 2024 Aug 20, 2025 Genetic testing for diagnosis and management of mental health disorders is considered investigational in... View
11.003.050 Genetic Testing for Epilepsy Mar 11, 2024 Mar 20, 2025 Epilepsy is a disorder characterized by unprovoked seizures. it is a heterogeneous condition that encompasses... View
11.003.051 Gene Expression Profiling and Protein Biomarkers for Prostate Cancer Management Oct 08, 2024 Oct 20, 2025 Use of gene expression analysis and protein biomarkers to guide management of prostate cancer is considered... View
11.003.052  Gene Expression Profiling and Protein Biomarkers for Prostate Cancer Managementt Sep 24, 2024 Sep 20, 2025 For individuals who have thyroid nodules without strong clinical or radiologic findings suggestive of... View
11.003.053 Whole Exome and Whole Genome Sequencing for Diagnosis of Genetic Disorders Apr 18, 2024 Apr 20, 2025 Standard whole exome sequencing, with trio testing when possible (see policy guidelines), may be considered... View
11.003.056 Genetic Testing for a Thalassemia Jul 10, 2024 Jul 20, 2025 Genetic testing to confirm a diagnosis of α-thalassemia is considered investigational. genetic testing... View
11.003.057 Genetic Testing for Fanconi Anemia Jan 15, 2025 Jan 20, 2026 Genetic testing for the diagnosis of fanconi anemia may be considered medically necessary when the... View
11.003.059 Genetic Testing for Hereditary Pancreatitis Mar 11, 2024 Mar 20, 2025 In chronic pancreatitis (cp), recurrent attacks of acute pancreatitis evolve into a chronic inflammatory... View
11.003.060  Genetic Testing for FLT3, NPM1, and CEBPA Variants in Cytogenetically Normal Acute Myeloid Leukemia Feb 20, 2024 Feb 20, 2025 Treatment of acute myeloid leukemia (aml) is based on risk stratification, primarily related to patient age... View
11.003.062 General Approach to Genetic Testing Jan 21, 2025 Jan 20, 2026 Genetic testing classified in one of the categories below may be considered medically necessary when all... View
11.003.063 BCR-ABL1 Testing in Chronic Myelogenous Leukemia and Acute Lymphoblastic Leukemia Dec 03, 2024 Nov 20, 2025 Chronic myelogenous leukemia bcr-abl1 qualitative testing for the presence of the fusion gene may be... View
11.003.064 Genetic Cancer Susceptibility Panels Using Next Generation Sequencing Dec 12, 2024 Nov 20, 2025 General genetic cancer susceptibility panel testing is considered investigational; however, when the... View

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