Human Growth Hormone

Recombinant human growth hormone (GH) is approved by the U.S. Food and Drug Administration (FDA) for various indications and is also proposed for various off-label indications, such as cystic fibrosis and treatment of older adults without documented growth hormone deficiency (GHD). This evidence review will focus specifically on various off-label indications to evaluate the net health outcome when human growth hormone is used compared with the standard therapy for these conditions.