Drug-coated balloons (DCBs) deliver antiproliferative agents directly to the coronary vessel wall via a semicompliant balloon coated with drugs (typically paclitaxel, sirolimus, or everolimus) embedded in a carrier matrix that rapidly diffuses into the vessel wall during inflation, without requiring permanent stent implantation. This approach provides localized drug delivery to inhibit neointimal hyperplasia while avoiding additional metallic layers.
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