Genetic Testing for Hereditary Hemochromatosis

Genetic testing for human hemochromatosis (HFE) gene variants may be considered medically necessary in an individual with abnormal serum iron indices indicating iron overload (see Policy Guidelines section).

Genetic testing for HFE gene variants may be considered medically necessary in individuals with a family history of hemochromatosis in a first-degree relative (see Policy Guidelines section).

Genetic testing for hereditary hemochromatosis for screening of the general population is considered investigational.