Genetic testing for genes associated with infantile- and early-childhood onset epilepsy syndromes in individuals with infantile- and early-childhood-onset epilepsy syndromes in which epilepsy is the core clinical symptom (see Policy Guidelines section) may be considered medically necessary if positive test results may:
Lead to changes in medication management; AND/OR
Lead to changes in diagnostic testing such that alternative potentially invasive tests are avoided; AND/OR
Lead to changes in reproductive decision making.
Genetic testing for epilepsy is considered investigational for all other situations.
