Coronary Computed Tomography Angiography With Selective Noninvasive Fractional Flow Reserve

Invasive coronary angiography (ICA) is clinically useful in stable ischemic heart disease when there is coronary artery obstruction that may benefit from revascularization. However, many individuals currently undergoing ICA will not benefit from revascularization. Therefore, if there are noninvasive alternatives to guide decisions about the use of ICA to spare individuals from unnecessary ICA, there is potential to improve health outcomes. Using noninvasive measurement of fractional flow reserve as part of a noninvasive imaging strategy may be beneficial to avoid the need for ICA.