Measurement of bone turnover markers is considered investigational to determine fracture risk in patients with osteoporosis or with age-related risk factors for osteoporosis.
Measurement of bone turnover markers is considered investigational to determine response to therapy in patients who are being treated for osteoporosis.
Measurement of bone turnover markers is considered investigational in the management of patients with conditions associated with high rates of bone turnover, including but not limited to Paget disease, primary hyperparathyroidism, and renal osteodystrophy.